Not trying to be a douche but aren't those the keys to any football game though?
1. Give QB time
2. Give RB room
3. Tight Coverage and Effective Blitzes
Okay, fine. I'll be "Browns-specific". :)
Defensively: I don't think that our front will have issues with a Browns line that is on the bad side of mediocre (I'm assuming they will be somewhowat improved). So I trust that we will contain the running attack just fine (not a big leap for our defense). Contain Edwards and Winslow--those are the closest things to playmakers that they have. I know that getting off the field on third down is a key for any game. But I mention it because I think it's the most frustrating aspect of our defense.
Offensively: Pass early. The Browns secondary sucks. Then pound them down with the run. I think we can open up the run via the pass on these guys. We come out guns firing.