at Minny
at SD
KC at home
at New York Jets
They could go 0-4 sure, but in all actuality, I expect them to end up being 2-2 during this, with losses to SD and Minny. From the way they've looked so far this year, I they'll have the focus to get the job done against scrub teams like KC and I think they just outmatch NY. But on that note, I believe SD and Minny are significantly better teams.
The only way I can see them losing all 4 is if they go into one of their traditional nosedives/meltdowns they've had a few times over the past few years, but they look like a different team at this point, personality wise than they have been for the last few years.